De mogelijke rol van Mg om EMV klachten tegen te gaan

maandag, 02 juni 2014 - Categorie: Onderzoeken

Bron: EMF refugees
2 juni 2014

In 2006, in my paper ''Do You Have Microwave/EMR Sickness?'' I wrote the following:

III. Microwaves, depending on their frequencies, have been known to effect an abnormal flux of calcium into or out of cells1 (Nair, 1989; Cleary, 1999; Dorothy, 19992; Amara, 2004). When there is an abnormal influx of calcium into mast cells, for example, they release histamine (Chakravarty, 1986, 1987). This is just one of the ways in which microwave exposure has been known to trigger or aggravate allergic reactions.3


1 ''Moreover, Nair and Cleary have reported, that the flux of positively charged sodium, calcium and potassium ions across cell membrane can also be affected by radio-frequency exposure, over a wide range of frequencies (27 MHz to 10 GHz)'' (Amara, et al, 2004)

2 ''Dr. Blackman has conducted far more experiments in his laboratory on this influx/efflux than anyone else. They have shown that calcium ion alteration occurs at particular carrier frequencies, particular signal strengths, particular modulation frequencies and in particular temperature ranges, but not in others which lie between them. After summarising these hundreds of experiments Carl Blackman stated that EMR must be treated as chemicals (plural) because we have made the mistake of treating it as a single chemical looking for single effects across the whole spectrum, when it is clear that the effects are very significant and occur at particular combinations of variables, but do not occur at a nearby different combination'' (Dorothy 1999).

3 ''Attempting to explain a 25% increase in asthma and a 5% increase in asthma-related death rates throughout rapidly mobilizing metropolitan Sydney, Franch found that the production of histamine, which triggers bronchial spasms, is nearly doubled after exposure to mobile phone transmissions. Cell phones also reduce the effectiveness of anti-asthmatic drugs, and retard recovery from illness'' (Thomas 2005).

In fact, the fact that EMFs can indeed cause an influx of calcium into the cell has become the cornerstone of Dr. Martin Pall's revised theory entailing nitric oxide, superoxide, peroxynitrite, and oxidative stress :

Due to numerous anecdotal accounts of people with both CFS (Chronic Fatigue Syndrome) and ES (Electro-sensitivity) improving with magnesium supplements .

Met aanbeveling Mg-citraat en Mg-glycinaat te gebruiken (200 - 400 mg per dag). . ,

I started ''wondering'' where magnesium fit into this equation and I started wondering further if magnesium might in fact be acting as a VGCC blocker. A quick google search confirmed this supposition:

Magnesium ions (Mg2+) bind to the C-terminal EF-hand to inhibit CaV1.2 channels, thereby reducing Ca2+ influx to maintain the intracellular Ca2+ at low levels77. Supplement of Mg2+ during global ischemia resulted in myocardial protection and improved functional recovery78.

. . . Intracellular free magnesium (Mg(i)) inhibits L-type Ca(2+) currents through Ca(V)1.2 channels in cardiac myocytes, but the mechanism of this effect is unknown. . . . These results support a novel mechanism linking the COOH-terminal EF-hand with modulation of Ca(V)1.2 channels by Mg(i). Our findings expand the repertoire of modulatory interactions taking place at the COOH terminus of Ca(V)1.2 channels, and reveal a potentially important role of Mg(i) binding to the COOH-terminal EF-hand in regulating Ca(2+) influx in physiological and pathophysiological states.

. . . the use of magnesium (magnesium supplemented potassium icardioplegia) has been shown to provide superior myocardial protection during global ischemia and to allow for enhanced post-ischemic functional recovery. The cardioprotective mechanisms of magnesium supplemented potassium cardioplegia which allow for decreased morbidity and mortality in the cardiac surgical patient has been shown to act at the level of the sarcolemma, mitochondria and the nucleus. and may be associated with myocardial gene expression in the aged heart. In this report these mechanisms are reviewed.

Since EMFs can -- via the opening of VGCC -- cause a calcium influx into cells stimulating the release of histamine from Mast Cells, and magnesium has a blocking effect on this, it might also be postulated that magnesium might also have the potential to act as a natural antihistamine in down-regulating calcium influx and also histamine release. And there is apparently evidence supporting this ''speculation'':

There is also anecdotal evidence suggesting that antihistamines do help with CFS:



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