Prenatal exposure to 900-megahertz electromagnetic field on rat testicle
woensdag, 09 oktober 2013 - Categorie: Onderzoeken
Bron: www.ncbi.nlm.nih.gov/pubmed/24095929?dopt=Abstract .
1 okt. 2013
Reprod Toxicol. 2013 Oct 1. pii: S0890-6238(13)00352-3. doi: 10.1016/j.reprotox.2013.09.006. (Epub ahead of print)
The effect of prenatal exposure to 900-megahertz electromagnetic field on the, 21-old-day rat testicle.
Hancı H, Odacı E, Kaya H, Aliyazıcıoğlu Y, Turan I, Demir S, Colakoğlu S.
Department of Histology and Embryology, School of Medicine, Karadeniz Technical, University, Trabzon, 61080, Turkey.
Abstract
The aim of this study was to investigate the effect of exposure to a 900-megahertz electromagnetic field (EMF) in the prenatal term on the 21-old-day rat testicle. Pregnant rats were divided into control (CG) and EMF (EMFG) groups. EMFG was exposed to 900-megahertz EMF during days 13-21 of pregnancy. Newborn CG rats were obtained from the CG and newborn EMFG (NEMFG) rats from the EMFG. Testicles were extracted at postnatal day 21. Lipid peroxidation and DNA oxidation levels, apoptotic index and histopathological damage scores were compared. NEMFG rats exhibited irregularities in seminiferous tubule basal membrane and epithelium, immature germ cells in the lumen, and a decreased diameter in seminiferous tubules and thickness of epithelium. Apoptotic index, lipid peroxidation and DNA oxidation were higher in NEMFG rats than in NCG.
21-day-old rat testicles exposed to 900-megahertz EMF in the prenatal term may be adversely affected, and this effect persists after birth.
Copyright © 2013. Published by Elsevier Inc.
KEYWORDS:
Apoptosis, Electromagnetic field, Rat, Testicle
PMID: 24095929 (PubMed - as supplied by publisher)
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