Frankrijk: Neurobiologische effecten GSM-straling op rattenbrein leeftijdsafhankelijk
donderdag, 19 april 2012 - Categorie: Onderzoeken
Bron: Experimental Gerontology 2012 Apr 6.
Effects of 900MHz radiofrequency on corticosterone, emotional memory and neuroinflammation in middle-aged rats.
Bouji M, Lecomte A, Hode Y, de Seze R, Villégier AS.
Unité de Toxicologie Expérimentale, Institut National de l'Environnement Industriel et des Risques (INERIS). Parc Technologique ALATA, BP no. 2, 60550 Verneuil-en-Halatte, France.
The widespread use of mobile phones raises the question of the effects of electromagnetic fields (EMF, 900MHz) on the brain. Previous studies reported increased levels of the glial fibrillary acidic protein (GFAP) in the rat's brain after a single exposure to 900MHz global system for mobile (GSM) signal, suggesting a potential inflammatory process.
While this result was obtained in adult rats, no data is currently available in older animals. Since the transition from middle-age to senescence is highly dependent on environment and lifestyle, we studied the reactivity of middle-aged brains to EMF exposure.
We assessed the effects of a single 15min GSM exposure (900MHz; specific absorption rate (SAR)=6W/kg) on GFAP expression in young adults (6week-old) and middle-aged rats (12month-old). Brain interleukin (IL)-1β and IL-6, plasmatic levels of corticosterone (CORT), and emotional memory were also assessed.
Our data indicated that, in contrast to previously published work, acute GSM exposure did not induce astrocyte activation.
Our results showed an IL-1β increase in the olfactory bulb and enhanced contextual emotional memory in GSM-exposed middle-aged rats, and increased plasmatic levels of CORT in GSM-exposed young adults.
Altogether, our data showed an age dependency of reactivity to GSM exposure in neuro-immunity, stress and behavioral parameters. Reproducing these effects and studying their mechanisms may allow a better understanding of mobile phone EMF effects on neurobiological parameters.
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