USA: Mobiele telefonie verstoort hersenmetabolisme.
zaterdag, 02 april 2011 - Categorie: Onderzoeken
Geplaatst 23 febr. 2011
Updated 2 april 2011 met de volgende link (video met Nederlandse ondertiteling):
Bron: JAMA Journal of the American Medical Association 22 febr. 2011
Effects of Cell Phone Radiofrequency Signal Exposure on Brain Glucose Metabolism
1. Nora D. Volkow, MD;
2. Dardo Tomasi, PhD;
3. Gene-Jack Wang, MD;
4. Paul Vaska, PhD;
5. Joanna S. Fowler, PhD;
6. Frank Telang, MD;
7. Dave Alexoff, BSE;
8. Jean Logan, PhD;
9. Christopher Wong, MS
+ Author Affiliations
Author Affiliations: National Institute on Drug Abuse, Bethesda, Maryland (Dr Volkow);
National Institute on Alcohol Abuse and Alcoholism, Bethesda (Drs Volkow, Tomasi, nd Telang and Mr Wong); and
Medical Department, Brookhaven National Laboratory, Upton, New York (Drs Wang, Vaska, Fowler, and Logan and Mr Alexoff).
The dramatic increase in use of cellular telephones has generated concern about possible negative effects of radiofrequency signals delivered to the brain. However, whether acute cell phone exposure affects the human brain is unclear.
To evaluate if acute cell phone exposure affects brain glucose metabolism, a marker of brain activity.
Design, Setting, and Participants
Randomized crossover study conducted between January 1 and December 31, 2009, at a single US laboratory among 47 healthy participants recruited from the community. Cell phones were placed on the left and right ears and positron emission tomography with (18F)fluorodeoxyglucose injection was used to measure brain glucose metabolism twice, once with the right cell phone activated (sound muted) for 50 minutes (on condition) and once with both cell phones deactivated (off condition). Statistical parametric mapping was used to compare metabolism between on and off conditions using paired t tests, and Pearson linear correlations were used to verify the association of metabolism and estimated amplitude of radiofrequency-modulated electromagnetic waves emitted by the cell phone. Clusters with at least 1000 voxels (volume >8 cm3) and P < .05 (corrected for multiple comparisons) were considered significant.
Main Outcome Measure
Brain glucose metabolism computed as absolute metabolism (mumol/100 g per minute) and as normalized metabolism (region/whole brain).
Whole-brain metabolism did not differ between on and off conditions. In contrast, metabolism in the region closest to the antenna (orbitofrontal cortex and temporal pole) was significantly higher for on than off conditions (35.7 vs 33.3 mumol/100 g per minute; mean difference, 2.4 95% confidence interval, 0.67-4.2; P = .004). The increases were significantly correlated with the estimated electromagnetic field amplitudes both for absolute metabolism (R = 0.95, P < .001) and normalized metabolism (R = 0.89; P < .001).
In healthy participants and compared with no exposure, 50-minute cell phone exposure was associated with increased brain glucose metabolism in the region closest to the antenna. This finding is of unknown clinical significance.
Voor het originele abstract zie:
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