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vrijdag, 28 mei 2010 - Categorie: Onderzoeken

Bron: Published in: Environ Health Perspect 2009

Microwaves from Mobile Phones Inhibit 53BP1 Focus Formation in Human Stem Cells Stronger than in Differentiated Cells: Possible Mechanistic Link to Cancer Risk.

By: Belyaev I, Markova E, Malmgren L

Aim of study (according to author)
To study whether microwaves from GSM or UMTS mobile telephones induce double-strand breaks or affect double-strand break DNA repair in stem cells or fibroblasts.

Main outcome of study (according to author)
The data showed that microwave exposure inhibited the formation of 53BP1 foci in human primary fibroblasts and mesenchymal stem cells. The GSM carrier frequency (915 MHz) and UMTS frequency band (1947.4 MHz) were effective for both cell types. Exposure at 905 MHz did not inhibit 53BP1 foci formation in differentiated cells, either fibroblasts or lymphocytes (as found in a previous study, see Belyaev et al. 2009), whereas some effects were seen in stem cells at 905 MHz (statistically not significant trend to foci inhibition). Contrary to fibroblasts, stem cells did not adapt to chronic exposure during two weeks (i.e. foci inhibition was still present).

In conclusion, the data indicate that stem cells are more sensitive to microwave exposure than differentiated human primary fibroblasts (or lymphocytes as shown in the previous study). The fact that stem cells are more sensitive to microwave exposure and react to more frequencies than do differentiated cells may be important for cancer risk assessment and indicate that stem cells are the most relevant cellular model for validating safe mobile communication signals.

Voor een uitgebreider abstract zie: .

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