Zweedse studie: ''Cell membrane is an important target for electromagnetic field effects''
maandag, 03 november 2008 - Categorie: Onderzoeken
Bron: The Environmentalist 2008: in press ( journal not peer reviewed )
Exposure to radiation from global system for mobile communications at 1,800 MHz significantly changes gene expression in rat hippocampus and cortex. med./biol.
By: Nittby H, Widegren B, Krogh M, Grafström G, Berlin H, Rehn G, Eberhardt J, Malmgren L, Perrson B, Salford L
Aim of study (according to author)
To study whether exposure to the irradiation from a GSM mobile phone at 1800 MHz has an effect upon the gene expression pattern in rat brain cortex and hippocampus.
8 male rats were assigned to an exposure group (n=4) and a sham exposure group (n=4). The SAR-level for the brain was with 30 mW/kg below the limit for mobile phone emissions set by ICNIRP.
investigated material: DNA/RNA (in vitro)
investigated organ system: brain/CNS
time of investigation: after exposure
Main outcome of study (according to author)
The genes did not significantly discriminate between exposed and sham exposed animals. The gene oncology analysis of the differentially expressed genes of both groups revealed four highly significant altered gene categories in both cortex and hippocampus (transmembrane receptor activity, receptor activity, cell surface receptor linked signal transduction and G-protein coupled receptor signaling pathway).
Most of these categories are connected with membrane functions what indicates that the cell membrane is an important target for electromagnetic field effects.
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