Protective effects of β-glucan against oxidative injury induced by 2.45-GHz EMR in skin tissue

Bron: www.ncbi.nlm.nih.gov/pubmed/22237725
Arch Dermatol Res. 2012 Sep;304(7):521-7. doi: 10.1007/s00403-012-1205-9. Epub 2012 Jan 12.

Protective effects of β-glucan against oxidative injury induced by 2.45-GHz electromagnetic radiation in the skin tissue of rats

Ceyhan AM 1, Akkaya VB, Güleçol ŞC, Ceyhan BM, Özgüner F, Chen W.

1 Department of Dermatology, Medical Faculty, Suleyman Demirel University, 32200, Cunur, Isparta, Turkey. amuratceyhan@yahoo.com

Abstract
In recent times, there is widespread use of 2.45-GHz irradiation-emitting devices in industrial, medical, military and domestic application. The aim of the present study was to investigate the effect of 2.45-GHz electromagnetic radiation (EMR) on the oxidant and antioxidant status of skin and to examine the possible protective effects of β-glucans against the oxidative injury. Thirty-two male Wistar albino rats were randomly divided into four equal groups: control; sham exposed; EMR; and EMR + β-glucan. A 2.45-GHz EMR emitted device from the experimental exposure was applied to the EMR group and EMR + β-glucan group for 60 min daily, respectively, for 4 weeks. β-glucan was administered via gavage at a dose of 50 mg/kg/day before each exposure to radiation in the treatment group. The activities of antioxidant enzymes, superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT), as well as the concentration of malondialdehyde (MDA) were measured in tissue homogenates of the skin. Exposure to 2.45-GHz EMR caused a significant increase in MDA levels and CAT activity, while the activities of SOD and GSH-Px decreased in skin tissues. Systemic β-glucan significantly reversed the elevation of MDA levels and the reduction of SOD activities. β-glucan treatment also slightly enhanced the activity of CAT and prevented the depletion of GSH-Px activity caused by EMR, but not statistically significantly. The present study demonstrated the role of oxidative mechanisms in EMR-induced skin tissue damages and that β-glucan could ameliorate oxidative skin injury via its antioxidant properties.


Met de volgende toelichting van John Weigel

Is your skin aging prematurely or are you noticing skin problems around Wi-Fi?

A study found that exposure to 2.45-GHz (Wi-Fi) electromagnetic radiation for 60 minutes daily for 4 weeks at 64mW/kg SAR (FCC limit is 80mW/kg SAR for whole body exposure, so exposure was below FCC limit) caused a statistically significant decrease in the activity of antioxidant enzymes dismutase (SOD) (p<0.01) and glutathione peroxidase (GSH-Px) (p<0.05) in skin tissues. Levels of malondialdehyde (MDA), an indicator of oxidative stress, increased significantly (p<0.001). The antioxidant supplement β-glucan significantly reversed the elevation of MDA levels and the reduction of SOD activities. “The present study demonstrated the role of oxidative mechanisms in EMR-induced skin tissue damages and that β-glucan could ameliorate oxidative skin injury via its antioxidant properties.”

www.ncbi.nlm.nih.gov/pubmed/22237725

Ceyhan AM, Akkaya VB, Güleçol ŞC, Ceyhan BM, Özgüner F, Chen W. Protective effects of β-glucan against oxidative injury induced by 2.45-GHz electromagnetic radiation in the skin tissue of rats. Arch Dermatol Res. 2012 Sep;304(7):521-7

Glutathione

A lot of studies show a decrease in glutathione or glutathione enzymatic activity from exposure to wireless radiation. Why is glutathione important? It is the main antioxidant in your body and produced by your liver. People take glutathione by mouth for treating cataracts and glaucoma, preventing aging, treating or preventing alcoholism, asthma, cancer, heart disease(atherosclerosis and high cholesterol), hepatitis, liver disease, diseases that weaken the body’s defense system (including AIDS and chronic fatigue syndrome), memory loss, Alzheimer’s disease, osteoarthritis, and Parkinson’s disease. Glutathione is also used for maintaining the body’s defense system (immune system) and fighting metal and drug poisoning.

www.webmd.com/vitamins-supplements/ingredientmono-717-GLUTATHIONE.aspx?activeIngredientId=717&activeIngredientName=GLUTATHIONE

In short, it is a very important chemical in your body, and one that you don't want decreased levels of if you want to stay healthy.



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