StopUMTS Logo
how to get rid of moles 
Zoeken
   
Voorlichting
16/01/18Toon : de 'slimme' thermo
14/01/18Medical Dictionary; micro
Artikelen
14/01/18Can Cell Phones Cause Fem
14/01/18Wetenschappers binden str
12/01/18Apple: Open letter from J
12/01/18Studenten die vaker met s
08/01/18Zonnepanelen; Solar Panel
06/01/18FCC geeft vergunning voor
Berichten Nederland
18/01/18Unlimited 4G voor thuis g
17/01/18Vergaderlocatie / cursusr
14/01/18Ziek van Straling; Fotose
12/01/18Stripheldenbuurt wil geen
12/01/18Stijging aantal euthanasi
Berichten België
18/01/18Aartselaar / Reet: Buren
10/01/18Vereniging ElektroHyperSe
Berichten Internationaal
15/01/18Frankrijk pakt belabberde
12/01/18Oostenrijk: Richtlijnen v
12/01/18Frankreich verordnet Stra
09/01/18USA: CDPH Cell Phone Safe
Ervaringen | Appellen/oproepen
15/01/18Ziekmakende ervaringen me
12/01/18Soms is tinnitus geen tin
12/01/18Bijnier probleem met smar
Onderzoeken
03/01/18EMFs + Wildlife
29/12/17Radiofrequency EMFs and H
19/12/17624 wetenschappelijke
Veel gestelde vragen
13/05/17Vakantie? Witte zo
10/07/16Zeven veel gestelde vrage
Juridische informatie
01/01/18Antennebeleid op basis va
15/12/17(Persbericht) Phonegate:
08/11/17InPower Movement: Early r
Oproepen
10/12/17Haarlem: Raadsmarkt ZENDM
11/11/17Cursus ‘Straling meten
29/10/17Petitie: Geen uitbreiding
Folders
10/09/17Brochures, folders, websi
29/04/16USA: Meer dan 50 tips voo
Briefwisselingen | Archief: 2008, 2005
18/01/18Brief naar de gemeente Ut
10/07/17Brief naar de gemeente C.
Illustraties
 Algemeen
 Fotoalbum zendmasten
 Wetenschappelijke illustraties
Microwave Radiation Injures Microvasculature Through Inducing Endoplasmic Reticulum Stress    
Ga naar overzicht berichten in: Onderzoeken

Microwave Radiation Injures Microvasculature Through Inducing Endoplasmic Reticulum Stress
maandag, 31 augustus 2015 - Dossier: Algemeen


Bron: onlinelibrary.wiley.com/doi/10.1111/micc.12122/abstract

Li Y, Qu X, Wang X, Liu M, Wang C, Lv Z, Li W, Tao T, Song D, Liu X. Microwave radiation injures microvasculature through inducing endoplasmic reticulum stress. Microcirculation 21: 490–498, 2014.

1Department of Pathophysiology, Chinese PLA General Hospital, Beijing, China
2State Key Laboratory of Kidney Disease, Chinese PLA General Hospital, Beijing, China
3Outpatient Department, Fourth Military Medical University, Xi'an, China

Keywords:
microwave radiation;microvasculature;microvascular endothelial cell;apotosis;endoplasmic reticulum stress
Abstract
Objective
The study aimed to investigate the effect of microwave radiation on microvasculature as well as the underlying mechanisms.

Methods
Sprague Dawley rats were exposed to microwave radiation. Microvascular diameters, flow velocity, blood perfusion, and permeability were measured. Cultured endothelial cells from microvessels were subjected to microwave radiation. Cytoskeleton, apoptosis, protein synthesis, and the markers of endoplasmic reticulum stress including 78-kDa glucose-regulated protein and calreticulin in endothelial cells were examined.

Results
Microwave radiation decreased microvascular diameters and blood perfusion, and increased the permeability of microvessles. And microwave radiation induced the formation of stress fibers, apoptosis, and LDH leakage from microvascular endothelial cells. Also, when microvascular endothelial cells were exposed to microwaves, protein synthesis was significantly elevated. We found that upon microwave radiation, the expression of 78-kDa glucose-regulated protein and calreticulin were greatly upregulated in microvascular endothelial cells. We also investigated possible signaling pathways for endoplasmic reticulum stress-initiated apoptosis. C/EBP homologous protein (CHOP) pathway was activated in microvascular endothelial cells exposed to microwaves.

Conclusions
Microwave radiation induces microvascular injury by triggering the apoptotic pathway of endoplasmic reticulum stress.


Ga terug naar het hoofdmenu
Afdrukken | Vragen | RSS | Disclaimer