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Franse studie: Niet overmatig opwarmende radiofrequente straling geeft verandering DNA sperma. Bron: Gynecol Obstet Fertil. 2008 Oct 27. Epub ahead of print Het onderhavige onderzoek gaat over het herkennen van fouten in DNA van sperma. De onderzoekers schrijven dat DNA van sperma ook kan veranderen onder invloed van radiofrequente velden, waarbij het werkingsmechanisme onduidelijk is. Het is interessant dat de onderzoekers dit stellen, kennelijk achten zij wetenschappelijk voldoende aangetoond dat radiofrequente velden, niet-thermisch en niet-ioniserend, toch DNA kunnen veranderen. Causes and clinical implications of sperm DNA damages.Article in French Hazout A, Menezo Y, Madelenat P, Yazbeck C, Selva J, Cohen-Bacrie P. Service de gynécologie-obstétrique, maternité Aline-de-Crépy, hôpital Bichat-Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France. Numerous recent studies involve DNA damages associated with poor fertilization rates, early embryo development defect, and poor quality of conceptus following Assisted Reproductive Technologies (ART). The authors denounce a particularly high rate of miscarriages and childhood cancer or dominant genetic mutations such as achondroplasia, Apert syndrome or aberrant gene imprinting such as Angelman and Beckwith Wiedeman syndromes. Gametes DNA defects have numerous origins which are difficult to determine; they are known to involve hypomethylation, oxydative stress and environmental factors.(adducts formation). DNA defect is also linked to a more or less delayed apoptotic phenomenon. Exposure to radiations or radiofrequency electromagnetic emissions can also induce DNA alterations into the spermatozoa of infertile men. Although the underlying mechanisms are unclear, these DNA defects have obvious consequences on reproduction of mammalian species. Detection of such anomalies before ART, are an important step toward developing strategies for clinical management according to the aetiology. Voor het originele abstract zie: www.ncbi.nlm.nih.gov/pubmed/18964175?dopt=AbstractPlus .
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