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In Vivo significante DNA-schade gevonden Gandhi G, A. Genetic damage in mobile phone users: some preliminary findings. Indian J Hum Genet serial online 2005 cited 2006 Jun 2;11:99-104. Available from: www.ijhg.com/article.asp?issn=0971-6866;year=2005;volume=11;issue=2;spage=99;epage=104;aulast=Gandhi Dit is een van de eerste onderzoeken waar gekeken is naar In Vivo (in levende proefmensen/dieren ipv in petri-schaaltjes zoals bij In Vitro) effecten van blootstelling aan straling. Slechts bij In Vivo onderzoek is het mogelijk om inzicht te krijgen in de effecten die daadwerkelijk optreden in een levend organisme dat gekenmerkt wordt door extreem complexe biologische processen. Een sterke correlatie tussen het gebruik van mobiele telefoons en genetische schade is gevonden. Een ander interessant In Vivo onderzoek is die waarbij gekeken is naar de effecten op rode bloedcellen van mensen die korte tijd (20 seconden) aan de straling van mobiele telefoons blootgesteld zijn. Zie UMTS%20in%20de%20media/275 . Hieronder volgt de Abstract/samenvatting in het Engels. Het complete verslag is te lezen op www.ijhg.com/article.asp?issn=0971-6866;year=2005;volume=11;issue=2;spage=99;epage=104;aulast=Gandhi . BACKGROUND: The impact of microwave (MW)/radio frequency radiation (RFR) on important biological parameters is probably more than a simply thermal one. Exposure to radio frequency (RF) signals generated by the use of cellular telephones have increased dramatically and reported to affect physiological, neurological, cognitive and behavioural changes and to induce, initiate and promote carcinogenesis. Genotoxicity of RFR has also been reported in various test systems after in vitro and/or in vivo exposure but none in mobile phone users. AIMS: In the present study, DNA and chromosomal damage investigations were carried out on the peripheral blood lymphocytes of individuals using mobile phones, being exposed to MW frequency ranging from 800 to 2000 MHz. METHODS: DNA damage was assessed using the single cell gel electrophoresis assay and aneugenic and clastogenic damage by the in vivo capillary blood micronucleus test (MNT) in a total of 24 mobile phone users. RESULTS: Mean comet tail length (26.76 ± 0.054 mm; 39.75% of cells damaged) in mobile phone users was highly significant from that in the control group. The in vivo capillary blood MNT also revealed highly significant (0.25) frequency of micronucleated (MNd) cells. CONCLUSIONS: These results highlight a correlation between mobile phone use (exposure to RFR) and genetic damage and require interim public health actions in the wake of widespread use of mobile telephony.
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